Probably one of the most underrated strategies of Book of Dead Slot is utilizing the betting on one line strategy. It might seem counter-intuitive initially to be betting on a single line with a multiline slot, but there is a strategy behind this. With Book of Dead Slot, most of your wins mostly come from the bonus. 

This strategy operates because you bet your maximum amount on just one line with coins at max or half max. You keep spinning until you get the bonus (which you can actually trigger no matter where the scatters land). Your net spend per spin is actually lessened because you are only winning on one win line, but if the bonus drops in, your special expanding symbol triggers off all of the normal paylines. It becomes is even juicier when you remember that your coin size is larger than you would regularly use, so your wins are hugely inflated. 

Of course this strategy comes with its two downsides. First, betting on one line implies that the only time you can ever win anything in the base game is when it lands on the center line. If you do get 3 symbols in a row, however, the returning pay is actually quite substantial, but it won’t happen very often. The second issue with this strategy on the Book of Dead Slot is that you could end up spinning for an extended period before you get a bonus.